The prokinetic agents in this class include bethanechol, which was used to treat heartburn and gastroparesis, a condition that causes partial paralysis in your stomach.

Discussion . To date, six other meta-analyses of prokinetic agents for treatment of FD have been reported ( Table 2). [43,44,45,46,47,48] In terms of the agents investigated and the scope of the ...

Medically reviewed by Lindsay Cook, PharmD Several available over-the-counter (OTC) and prescription drugs can help manage ...

Prokinetic agents produce an increase in LES tone, which, along with acid suppression, plays a key role in bringing reflux under control. Cisapride, ...

TZP-102 is a novel, orally administered prokinetic agent that acts by a mechanism distinct from previously developed products for gastrointestinal (GI) motility disorders. TZP-102 is a ...

In contrast, for the two most effective study doses, fewer than 5% of TZP-101 patients experienced nausea or vomiting, consistent with the strong GI prokinetic activity of TZP-101 and early ...

Many common drugs, including some prokinetic, antibiotic and anti-psychotic medications, can change how the heart’s electrical system functions. This is known as QT-prolongation, ...

Methods Selection of Studies. Studies on prokinetic agents, including metoclopramide, domperidone, trimebutine, cisapride, itopride and mosapride, in patients with FD were identified by ...