近日，中山大学医学院徐培教授团队在PML小体介导抗病毒天然免疫的研究中取得新进展，相关研究发表在微生物学权威学术期刊mBio（中科院一区，JCR ...

聚焦于急性早幼粒细胞白血病 （acute promyelocytic leukemia，APL） 发病相关的潜在功能性非编码区突变，王侃侃团队通过整合24例 APL 患者的配对全基因组 ...

Synchronous twin malignancies, defined as the simultaneous occurrence of two distinct primary cancers in the same patient, ...

The advent of all-trans-retinoic acid (ATRA) and its combination with anthracycline-containing chemotherapy have contributed in the past 2 decades to optimize the antileukemic efficacy in acute ...

Cite this: Acute Promyelocytic Leukemia: A Subset of Acute Myeloid Leukemia - Medscape - Apr 14, 2022. Tables. Authors and Disclosures. Authors and Disclosures Experts Gail J. Roboz, MD.

Researchers at Zhejiang University School of Medicine have identified a single point mutation in the normal PML gene that can block the effect of arsenic trioxide, a frontline drug for acute ...

Acute promyelocytic leukemia (APL) is rare in children, representing 4% to 8% of childhood acute myeloid leukemias and approximately 10% of all APLs; it is characterized by a higher incidence of ...

We studied acute promyelocytic leukemia (APL) with the t(15;17) translocation that developed after treatment of breast or laryngeal cancer with chemotherapeutic agents that poison topoisomerase II.

Untreated acute promyelocytic leukaemia is treated with ATRA plus chemotherapy. 3.2 Current treatment for untreated, low-to-intermediate risk acute promyelocytic leukaemia is all-trans-retinoic acid ...