Scientists at Université de Montréal and its affiliated Montreal Clinical Research Institute (IRCM) have uncovered unique roles for a protein complex in the structural organization and function of ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

Protein-Protein Interactions (PPIs) are critical for biological systems to function properly. Strong interactions maintain structural integrity and function, whereas weaker interactions enable ...

Artificial intelligence (AI) is transforming how scientists understand proteins—these are working molecules that drive nearly every process in the human body, from cell growth and immune defense to ...

Researchers discovered a new function for a common protein in the brain -- a development that sheds new light on the mysteries of the mind and holds promising implications for the treatment of memory ...

Mitochondria possess their own mRNA translation system, mediated by specialized mitoribosomes. Dysregulation of mitochondrial translation disrupts metabolic homeostasis and is linked to various ...

Researchers found that TEX38 and ZDHHC19 co-localize on the plasma membrane of spermatids and mediate S-palmitoylation of ARRDC5, a crucial protein for spermatogenesis. Disrupting either TEX38 or ...

GBA1 mutations alone do not explain lysosomal dysfunction in PD. Loss of endosomal recycling proteins cripple this lysosomal enzyme. Without a protein called COMMD3, cells spit out would-be lysosomal ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.