Profiling the proteins that cells are making is a staple of studies in biology, neuroscience and related fields because the proteins a cell is expressing at a given moment can reflect the functions ...

Data independent analysis and hyper reaction monitoring have recently emerged as new methods of mass spectrometry which address some of the shortcomings of traditional procedures. This review ...

The first-in-human phase 1/2 study of TSN1611, a highly selective KRAS G12D inhibitor, in patients with advanced solid tumors. Seizure-related homolog 6 (SEZ6) expression and ctDNA methylation ...

Plasma protein profiling may offer a more refined diagnostic tool for classifying mastocytosis subtypes and predicting disease course. The study emphasizes that mastocytosis is not solely driven by ...

Vaccination with survivin and PSMA-derived peptides for controlling biochemical recurrence in prostate cancer: A pilot study No significant financial relationships to disclose. This is an ASCO Meeting ...

This proteomics-driven approach to drug discovery improves target validation and uncovers insights into undruggable proteins, ...