The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...

The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.

New method accelerates protein engineering by using structural and evolutionary constraints in inverse folding models without training specialized AI systems. (Nanowerk News) A team of Chinese ...

From protein translation to mitosis, fundamental cellular processes are multifaceted and dynamic. Researchers seeking to understand the inner workings of a cell benefit from multidisciplinary ...

A team of researchers has developed a method that could transform the field of protein engineering. The new approach, called AI-informed Constraints for protein Engineering (AiCE), enables rapid and ...

Protein design is crucial for the treatment of human diseases, but traditional protein design methods have some limitations. Site-directed mutagenesis is highly dependent on the physiological ...

University of Missouri researchers have released the world's largest collection of protein models with quality assessment—a groundbreaking new resource that could accelerate drug development for ...

Protein drugs feature significant advantages over small molecule therapeutics, including low toxicity, high specificity, and development speed. However, the quality control requirements are ...

A group of Chinese scientists has created powerful new tools that allow them to edit large chunks of DNA with incredible accuracy—and without leaving any trace. Using a mix of advanced protein design, ...