The authors compare quality metrics of libraries from seven strand-specific RNA-seq methods in terms of complexity, strand specificity, evenness and continuity of coverage, and expression profiling.

RNA: The unknotted strand of life. ScienceDaily. Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2015 / 02 / 150202160657.htm. International School of Advanced Studies (SISSA).

Pictured is a computer-generated RNA structure tied in a trefoil knot. C. Micheletti et al. screened the several thousand RNA chains in the Protein Data Bank for the presence of knots. Only three ...

It had never been verified before: unlike other biopolymers, RNA, the long strand that is 'cousin' to DNA, tends not to form knots. The observation has been published in the journal PNAS by a ...

Cheng, L., et al. (2022) Cotranscriptional RNA strand exchange underlies the gene regulation mechanism in a purine-sensing transcriptional riboswitch.

The technology, which was described in a paper in Nature Communications in November, requires only one probe per RNA strand (DOI: 10.1038/s41467-024-54263-5).

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RNA, or ribonucleic acid, is a essential biological molecule that plays a crucial role in various cellular processes. It is a polymeric molecule composed of nucleotides, each containing a ribose sugar ...

RNA origami is a new method for organizing molecules on the nanoscale, making it possible to fabricate complicated shapes from a single strand of RNA. Unlike existing methods for folding DNA ...

Strand believes it has just the solution, building on research from Ron Weiss’s lab at the Massachusetts Institute of Technology. The company has solved the problem by controlling where the ...

Currently, the researchers have only been able to replicate roughly 17 percent of the RNA strand (roughly 30 out of 180 letters), but the team says there’s no reason they won’t achieve ...