He predicted that the restriction enzyme and the modification enzyme act on the same DNA sequence, called a recognition sequence. In this way, the bacterial cell's own self-defense mechanism ...

While Roberts pursued new restriction enzymes, others used them to sequence, map, clone, and manipulate genes. At the start of his tenure with Cold Spring Harbor Laboratory, Roberts originally ...

The discovery of restriction enzymes in the early 1970s heralded a new age in molecular biology. These enzymes recognize characteristic DNA sequences and cut them. Bacteria and Archaea can also use ...

This process is referred to as cloning. It uses restriction enzymes to cut the plasmid and the gene fragment at sequence-specific locations that depend on the enzyme used. Then, enzymes called ligases ...

Their AI tool quantifies the likelihood of certain sequences or mutations appearing in nature. Fascinatingly, they discovered ...

Indeed, the enzyme “was most similar to bacterial restriction modification enzymes ... and they are largely concentrated on transposable element sequences, as well as some tandem repeats. Biochemist ...

meaning that the sequence reads the same forward and backward. HindIII, for example, is an H. influenzae restriction enzyme that recognizes the sequence 5'AAGCTT-3' (upper strand)/3'TTCGAA-5 ...