Skeletal muscle cells are prone to plasma membrane lesions under physiological levels of mechanical stress. To prevent cell death and to avoid muscle regeneration with concomitant depletion of stem ...
Figure 1: Loss of sarcolemma-localized nNOS leads to skeletal muscle vascular narrowings, decreased capillary perfusion and an exaggerated fatigue response after mild exercise in dystrophic and ...
Duchenne muscular dystrophy (DMD) is the most common muscular dystrophy diagnosed in childhood, with approximately 20,000 new cases reported each year. It is a progressive muscle disorder that results ...