Type IV secretion systems (T4SSs) comprise 12 protein components, VirB1–VirB11 and VirD4. VirB2 forms a pilus and is co-purified with VirB5. VirB4, VirB11 and VirD4 are ATPases powering pilus assembly ...

The research team’s scientific paper was published in the Journal of Clinical Investigation (JCI) and showed that 395 genes are differently expressed in the pancreatic islets in individuals with type ...

UB researchers have found that taking a fiber supplement can help patients with Type 2 diabetes boost their insulin secretion even after eating a high-fat, high-carbohydrate meal. The research was ...

Whether improved glucose control with hybrid closed-loop therapy can preserve C-peptide secretion as compared with standard insulin therapy in persons with new-onset type 1 diabetes is unclear. In a ...

In a trial involving youths with new-onset type 1 diabetes, intensive glucose control with hybrid closed-loop therapy for 24 months did not preserve C-peptide secretion as compared with standard ...

The gene BHLHE40 disrupts insulin secretion in hyperglycemia-induced hypoxic conditions, which could inform drug development for type 2 diabetes Type 2 diabetes (T2D) is a chronic metabolic disorder ...