撰文丨王聪编辑丨王多鱼排版丨水成文衰老（Aging）的主要特征表现为器官及生物体生理完整性与功能的逐步丧失。它也是衰老相关疾病的首要风险因素。最新研究进一步证实，细胞衰老（Cellular Senescence）是机体衰老（Organismal ...

第五届单细胞与空间组学论坛近日，南方医科大学南方医院研究团队在期刊《Advanced Science》上发表了研究论文，题为“PRELID1 and VDAC3 Coordinate a Senescence-Like State in Germinal Center B Cells to Promote IL-7–Driven Antitumor Immunity in Colorectal C ...

Our work highlights the need to study polyploidy and senescence in concert to understand their roles in aging, cancer, and ...

Postpartum breast cancer is diagnosed five to ten years after giving birth. It is associated with a higher risk of metastasis and a lower survival rate compared with women who have not been pregnant ...

Researchers have discovered that damage to the cell membrane promotes cellular senescence, or cell aging. Our cells are surrounded by a fragile membrane that's only 5 nanometers thick, 1/20 of a soap ...

As we age, our bodies change and degenerate over time in a process called senescence. Stem cells, which have the unique ability to change into other cell types, also experience senescence, which ...

Senescent cells, which are damaged and inflammatory, contribute significantly to aging. Researchers at the Max Planck Institute for Biology of Aging have found that worms can enter a senescent-like ...

Explore the risks of postpartum cancer and discover how cellular senescence affects breast tissue after pregnancy.

Cellular senescence—an irreversible cell-cycle arrest coupled with the production of pro-inflammatory secretions known as SASP—is now viewed as a central driver of musculoskeletal aging. Accumulation ...

In a recent study published in Nature Metabolism, researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis. Fibrogenesis is a defensive reaction to ...