the current view is that membrane-bound antigens are the predominant forms that initiate B-cell activation in vivo. Secondary lymphoid organs (SLOs), such as the lymph nodes and spleen ...

B-cell lymphoma is a type of blood cancer that affects the B lymphocytes of the immune system. They usually arise in the lymph nodes or in other lymphoid tissue, such as the spleen, bone marrow ...

"Most studies linking kidney disease with abnormal B cell response were either ... virus to trigger a germinal center (GC) response in the spleen, which is central to the development of protective ...