脾肿大（Splenomegaly, SM）是临床常见的体征，但其病因复杂多样，从血液系统恶性肿瘤到罕见遗传病均可能涉及。尽管常规检查可诊断大多数病例，仍有相当比例患者面临“不明原因脾肿大”的困境，导致诊断延迟甚至不必要的手术干预。

Splenomegaly is an enlarged spleen. This can cause stomach discomfort, decreased blood flow and filtering, and anemia. It can even lead to a ruptured spleen, so taking precautions and seeing a ...

Healthcare professionals consider splenomegaly when the spleen is anywhere from 12 to 20 centimeters (cm) (4.7 to 7.9 inches [in]) in length and weighs more than 400 grams (g) (0.88 pounds [lb]).

Infiltrative splenomegaly: Develops when substances that normally don’t enter the spleen, such as proteins and a form of glucose (sugar) called glycogen, enter the spleen and become trapped there.

Symptomatic splenomegaly, a frequent manifestation of myelofibrosis (MF), represents a therapeutic challenge. It is frequently accompanied by constitutional symptoms and by anemia or other ...

Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

In splenomegaly, the spleen retains too many platelets. When a person has splenomegaly, their spleen may be congested with platelets, and their blood may not have enough platelets.

Splenomegaly, or enlargement of the spleen, is common in patients with Philadelphia-negative myeloproliferative neoplasms, and it is associated with symptoms like early satiety and abdominal pain.

Since evaluation of splenomegaly still rests for the most part on physical examination however, it is believed that a technic often heretofore neglected in classic teaching should merit consideration.

In patients receiving iTNT, splenomegaly (P = 0.009) and older age (P = 0.033) were still the major predictive factors for G2-4 thrombocytopenia. Conclusions: In LARC patients, the addition of PD-1 ...

A secondary cohort of 104 patients (62 men, 42 women; mean age, 56 years) with end-stage liver disease underwent pre-liver transplant CT from January 2011 to May 2013.