Healthcare professionals consider splenomegaly when the spleen is anywhere from 12 to 20 centimeters (cm) (4.7 to 7.9 inches [in]) in length and weighs more than 400 grams (g) (0.88 pounds [lb]).

Splenomegaly is one of the characteristic signs of an overactive spleen. It can cause platelets to pool inside of your spleen and cause thrombocytopenia. Thrombocytopenia is when you have a low ...

In splenomegaly, the spleen retains too many platelets. When a person has splenomegaly, their spleen may be congested with platelets, and their blood may not have enough platelets.

Splenomegaly and associated symptoms such as abdominal pain compromise the quality of life in patients with myelofibrosis, 17,19 and alleviation of these aspects of myelofibrosis by INCB018424 is ...

Splenomegaly, or enlargement of the spleen, is common in patients with Philadelphia-negative myeloproliferative neoplasms, and it is associated with symptoms like early satiety and abdominal pain.

Symptomatic splenomegaly, a frequent manifestation of myelofibrosis (MF), represents a therapeutic challenge. It is frequently accompanied by constitutional symptoms and by anemia or other ...

Since evaluation of splenomegaly still rests for the most part on physical examination however, it is believed that a technic often heretofore neglected in classic teaching should merit consideration.

Did you know that certain medications can cause symptom of 'Splenomegaly'. Find these drugs listed on the page and be warned of similar symptoms as possible side-effects.

A secondary cohort of 104 patients (62 men, 42 women; mean age, 56 years) with end-stage liver disease underwent pre-liver transplant CT from January 2011 to May 2013.

Splenomegaly is an enlarged spleen. This can cause stomach discomfort, decreased blood flow and filtering, and anemia. It can even lead to a ruptured spleen, so taking precautions and seeing a ...

Infiltrative splenomegaly: Develops when substances that normally don’t enter the spleen, such as proteins and a form of glucose (sugar) called glycogen, enter the spleen and become trapped there.