Subgroup analyses are important elements of clinical trial results reporting. Only average results are reported in RCTs, and trial participants are frequently recruited from a heterogeneous population ...

The subgroup analysis of patients with advanced LPS was planned among other subgroup analyses in the statistical analysis plan of the main study. 18 A total of 143 patients with LPS (31.6% of the ...

Tozorakimab, an anti-IL-33 antibody, improves lung function and may reduce exacerbations in high-risk COPD patients, early ...

These subgroup analyses add to the existing evidence of bempedoic acid as an effective treatment for the reduction of cardiovascular risk. May 29, 2024 03:00 AM Eastern Daylight Time.

In the CPS-10 subgroup, the median overall survival was 23.0 months in the pembrolizumab–chemotherapy group and 16.1 months in the placebo–chemotherapy group (hazard ratio for death, ...

The algorithm is based on a formulation of subgroup fairness as fictitious play in a two-player zero-sum game between a Learner (the primal player) and an Auditor (the dual player). Finally, we ...

"In this subgroup analysis on tumor burden and focality from the ENVISION study, the overall CR rate was consistent, and a majority of patients maintained their response 12 months after achieving ...

AstraZeneca's experimental therapy anselamimab did not meet the main goal of a late-stage study for the treatment of a rare ...