Nobel laureate Shimon Sakaguchi reflects on the role of regulatory T cells in peripheral immune tolerance and how the cells ...

T cell therapy, which uses a patient's own immune cells to fight cancer, has emerged as a powerful way to treat lymphoma and ...

Sarah Bird is at the Institute of Cancer Research, London SM2 5NG, UK and at the Royal Marsden Hospital NHS Foundation Trust, London. Charlotte Pawlyn is at the Institute of Cancer Research, London ...

MIT and Harvard scientists have created engineered CAR-NK cells that can hide from the immune system and more effectively ...

The cancer drugs called PARP inhibitors have a puzzling reputation: even though they are treatment mainstays for multiple forms of cancer, they can damage cancer-killing T cells and disrupt the ...

CAR T-cell therapy has the potential to revolutionise how we treat certain types of cancer by genetically engineering someone’s own immune cells to attack the disease – but it is also cumbersome and ...

Acute myeloid leukemia (AML) cells under the microscope, in purple. There is a serious need for finding better ways to treat AML that comes back after initial treatment. Chimeric antigen receptor (CAR ...

HPV, a very common virus, is found to hijack the body's cells to directly drive skin cancer growth, even after surgeries and ...

One of the newest weapons that scientists have developed against cancer is a type of engineered immune cell known as CAR-NK (natural killer) cells. Similar to CAR-T cells, these cells can be ...

Cancer cells transfer mitochondria through nanotubes to healthy neighboring cells, turning them into tumor-supporting accomplices, a new study shows.

Scientists discovered that inhibiting the enzyme STK17B forces multiple myeloma cells into iron-driven death and makes ...