Northwestern University researchers have identified structural features in engineered cell receptors that correlate with ...

Scientists engineered T cells to protect instead of kill, potentially enabling targeted treatments for autoimmune disease and ...

The discovery of microbial-sensing proteins called Toll-like receptors is transforming ... generates antibody-secreting B cells and cytotoxic T cells that are specific and efficient at targeting ...

But scientists have now used human brain tissue donated by epilepsy patients to study the structure of GABAA receptors. These receptors are crucial molecules that help control the movement of ions in ...

Explore how T cell engagers could transform cancer and autoimmune treatments through promising trials and key collaborations.

Using protein structure prediction tools, researchers have uncovered receptor structure-function relationships to improve cell therapies.

Araç's lab has been working for 11 years to reveal the structure of full-length aGPCRs, hoping to learn how incoming signals are transmitted from outside to inside the cell. These receptors are ...

Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case ...