Scientists have long struggled to target proteins that lack defined structure and are involved in cancer, neurodegenerative disorders like Parkinson's disease, and other serious illnesses. Now, a new ...
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Trapping a single protein in a molecular cage: A new path to drug discovery for amyotrophic ...
Proteins often function in pairs or groups, concealing their internal connection points and making it difficult for ...
Designing drugs is a bit like playing with Polly Pocket. The vintage toy is a plastic clam shell that contains a multi-bedroom house, a skating rink, a disco dance floor, and other fun scenarios. Kids ...
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 ...
Peking University, June 1, 2025: To address the challenge of controlling protein activation in living animals for gain-of-function studies, researchers from Peking University led by Professors Chen ...
Origami is collaborating with Ipsen to develop molecules designed to remove or correct abnormal proteins in neurodegenerative diseases.
Textbooks often depict proteins in one conformation, but real life, as usual, is much messier. While some proteins have stable, unchanging structures, many others have intrinsically disordered regions ...
Protein engineering is a powerful biotechnological process that focuses on creating new enzymes or proteins and improving the functions of existing ones by manipulating their natural macromolecular ...
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