Transdifferentiation often involves finding triggers that erase a cell’s identity and give it another. Sometimes these are small chemicals that activate a developmental pathway. More often they’re ...

Researchers led by the University of Tsukuba have demonstrated transdifferentiation, an important process by which this reorganization occurs that holds promise for future treatments for vascular ...

Background: In lung adenocarcinomas (LUADs), lineage plasticity drives neuroendocrine (NE) and squamous cell (LUSC) transdifferentiation in the context of acquired resistance to targeted inhibition of ...

Transdifferentiation: Going Straight to the Source of Vascular Disease Researchers from the University of Tsukuba and the National Cerebral and Cardiovascular Center identify transdifferentiation ...

Moreover, alteration of drug resistance related SLC7A5, SLC3A2, and SLC25A24 genes was observed. Additionally, an enrichment analyses identified, among others, neuroendocrine transdifferentiation ...

Study reveals the mechanisms involved in the transdifferentiation of esophageal keratinocytes into columnar cells. Download PDF Copy; Reviewed. Reviewed by Emily Henderson, B.Sc. Apr 21 2021.

“Transdifferentiation occurs when an adult cell matures into another type of cell that is needed at that very moment, and it is generally an important step during regeneration,” Miglietta said.