Functioning brain cells need a functioning system for picking up the trash and sorting the recycling. But when the cellular sanitation machines responsible for those tasks, called lysosomes, break ...

New research, published today in the journal Science, shows how lysosomes — organelles that act like cells’ waste disposal system — respond to stress by becoming abnormally bloated, a process called ...

Enhanced FIB-SEM images of untreated cells and cells treated with Torin, which causes nutrient stress. The ER exit sites (magenta), ER (blue), mitochondria (green), and all lysosome-related organelles ...