脊髓灰质炎病毒(pv)的防控曾是全球公共卫生的重大挑战。虽然通过口服脊髓灰质炎疫苗(opv)的大规模接种，野生型脊髓灰质炎病毒(wpv)2型和3型已被宣布根除，但opv的遗传不稳定性导致疫苗衍生脊髓灰质炎病毒(vdpv)持续出现，成为脊髓灰质炎终结阶段的新挑战。

灭活的制造工艺，可完全杜绝vapp和vdpv的发生，具有减毒株+灭活的“双重安全保证”。 作为我国“十二五”期间医药卫生领域的重大标志性成果，2015年上市的SabinIPV成为全球消灭脊灰的里程碑式产品。

There have also been several instances of detection of VDPV in wastewater in New York and the U.K. And wild poliovirus -- once thought to be isolated in Pakistan and Afghanistan ...

VDPV will remain a risk as long as OPV is used, because it's OPV itself that creates the risk. The only way to put an end to that risk, forever, ...

In 2013, we observed two cases of prolonged VDPV infection in severely immunocompromised children who required intensive care in an oncology ward ().After 3 months of hospitalization in Patient 1 ...

Experts have warned that the eradication of polio is at risk because of continued outbreaks of the disease caused by the vaccine-derived virus.

A 10-month-old baby in Beed district, Maharashtra who was recently diagnosed of polio caused by the vaccine-derived poliovirus (VDPV) type 2 turns the spotlight on the shortcomings of using a live ...

In VDPV, the source of the virus is the vaccine itself. The oral polio vaccine called polio drops, which India deployed extensively to fight against polio, contain a live, attenuated or weakened ...

As per the WHO norms, the best way to cope with cases of NPAFP and VDPV is a synchronised switch from trivalent to bivalent Oral polio vaccine, which India has already done.

India News: An 11-month-old boy from Maharashtra's Beed district has been found infected with the vaccine derived polio virus (VDPV). This is the first such case ...