Researchers developed a scalable screening system that identified 13 novel VPS4B inhibitors while lowering costs and reagent consumption.

This study revealed two independent retrograde pathways: a sorting nexin–mediated pathway (orange) and a core retromer–mediated pathway (blue). In yeast, sorting nexins and the core retromer form a ...

Prof. Scott Emr, molecular biology, earned the 2021 Shaw Prize for Life Science and Medicine for unpacking the secrets of a set of proteins that are able to detect key molecular signals to transport ...