Autophagy—meaning "self-eating" in Greek—is a fundamental cellular mechanism that preserves cell health by recycling and degrading worn-out or dysfunctional components. Serving as an essential ...

A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

A complex cellular process called autophagy is the topic of a major new textbook which encapsulates over 30 years of research in this growing field of study. A complex cellular process called ...

Researchers suggest targeting ECM-mediated regulation of autophagy levels could be used to sensitize pancreatic cancer to FDA-approved therapies.

A feature of pancreatic cancer cells' surroundings determines whether they grow fast or become resistant to chemotherapy, a new study shows. The ability of these cancer cells to adapt quickly and ...

T stem cells normally undergo asymmetric cell division (left) whereby one daughter cell becomes a long-lived memory T cell. When autophagy is disrupted, both daughter cells inherit old mitochondria ...

In the complex world of cancer biology, the term ‘autophagy’ has transitioned from a niche scientific phrase to a focal point of investigation for both prevention and treatment. Derived from Greek, ...

Researchers at the Max Delbrück Center and the University of Oxford have found that a cellular housekeeping function called autophagy—by which cell components are broken down and recycled—plays a ...

Autophagy is essentially the "rubbish collection" of our cells. If there are problems in this process, which is so important for our health, diseases such as Parkinson's can result. In their latest ...