The intracellular level of cyclic-AMP is chiefly determined by the balance between its formation from 5′ATP by adenyl cyclase and its degradation to 5′AMP by a specific 3′5′ cyclic ...

Crtc3 was activated in response to catecholamine signals, when it reduced adenyl cyclase activity by upregulating the expression of Rgs2, a GTPase-activating protein that also inhibits adenyl ...