Most cases of cVDPV are caused by mutations in a strain of poliovirus called type 2. Right now, outbreaks are being tackled using the old vaccine for type 2 polio — which risks seeding further ...

There are troubling signs that the COVID-19 pandemic created new chances for diseases formerly in retreat—like polio and measles—to spread.

Polio has almost been eradicated. A field study demonstrates that a combination of focused science and epidemiology, and community-based integrated health approaches, are required to finish the job.

(Nearly all cVDPV is type 2, which was eradicated in 1999.) By using live vaccine containing only types 1 and 3, countries can maintain immunity to any persisting wild polio, while cutting off the ...

In countries affected by all three serotypes — wild type 1, wild type 3 and cVDPV type 2 — getting the vaccine mix right is critical, Rosenbauer says. In Nigeria, a combination of monovalent, bivalent ...

According to the report, the proportion of cVDPV cases caused by cVDPV1 increased from 3% in 2020 to 18% in 2022 following “a substantial decrease in global routine immunization coverage and ...

While cVDPV is derived, as the name suggests, from an oral polio vaccine, known as the Sabin vaccine, or OPV. Nigeria’s fight against polio.

Type 2 cVDPV (cVDPV2) now accounts for most of the cVDPV cases globally, and is a major challenge to achieving global eradication. In Nigeria, ...

VDPVs can cause paralytic polio in humans and have the potential for sustained circulation. VDPVs resemble WPVs biologically [3] and differ from the majority of vaccine-related poliovirus (VRPV ...

Africa: WHO Urges Government to Ensure That Stopping Circulating Vaccine Derived Polio Virus (CVDPV) Remains an Urgent Priority for the National Polio Programme. 25 October 2020.

A vaccine-derived strain of poliovirus that has spread in recent years is serious but it can be tackled with an existing vaccine, according to a new study published in the New England Journal of ...