【编辑推荐】本研究首次揭示酮内酯类抗生素Cethromycin通过靶向疟原虫顶质体（apicoplast）实现单剂量根治伯氏疟原虫（P. berghei）肝期感染的机制，其肝脏药物浓度达血浆440倍，60 mg/kg剂量（等效人类300 mg）可实现100%治愈率，为休眠期间日疟（P. vivax）根治提供了无需G6PD检测的安全替代方案。

Co announces Cethromycin at 300 mg once daily for seven days was well tolerated by subjects with hepatic impairment and subjects with normal hepatic function. The results suggest that no dose ...

Co announces positive results from Trial CL-06, the first of two Phase 3 clinical trials designed to assess the safety and effectiveness of cethromycin, a once-a-day antibiotic, for the treatment ...

Cethromycin Achieves Primary Endpoint in Pivotal Phase 3 Pneumonia Clinical Trial CHICAGO, June 21, 2007 -- Advanced Life Sciences Holdings, Inc. , today announced positive results from Trial CL ...

The small pharmaceutical company Advanced Life Sciences has moved a big step closer to providing doctors with a new tool to fight bacteria that have developed resistance to antibiotics. The ...

Cethromycin Achieves All Endpoints in Second Pivotal Phase III Trial for Treatment of Pneumonia Trial CL-05 Results Showed Cethromycin had 94.0% Clinical Cure Rate Compared to 93.8% Clinical ...

Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), today announced positive results from Trial CL07-001, a thorough QT study of the Company's novel once-a-day oral antibiotic, ...

The antibiotic, cethromycin, also has shown in test tube experiments that it can fight MRSA, the so-called superbug staph infection that has caused worries because of ...

In the next few months, a very big drug company and a very small one could face crucial verdicts on a new class of antibiotics. , whose antibiotic Ketek will be subject to hearings on Dec. 14 and ...

Defense Dept. exercises cethromycin option CHICAGO, March 23 (UPI) -- The U.S. Defense Department has exercised a contract option with Advanced Life Sciences Holdings Inc. to continue development ...

The drug, Cethromycin, likely will move toward regulatory approval later this year, the Woodridge-based company said. The primary market […] Skip to content. All Sections. Subscribe Now.