Lab-designed chimeric protein shows beneficial effects in animal models of Alzheimer's disease
A research team at the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has developed a new ...
来自MSN2 个月
Loosening chimeric antigen receptor's grip on T-regulatory cells improves function ...
A new paper from MUSC Hollings Cancer Center researchers is helping to reveal the "rules" for engineering chimeric antigen receptor (CAR) Tregs. Tregs, or T-regulatory cells, have shown promise in ...
Armed robbery in Revesby13 天
Chimeric Protein Shows Promise in Alzheimer's Models
A research team at the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) has developed a new protein capable of improving ...
The New England Journal of Medicine18 天
CD4+ T-Cell Lymphoma Harboring a Chimeric Antigen Receptor Integration in TP53
Malignant T-cell transformation after chimeric antigen receptor (CAR) T-cell therapy has been described, but the contribution of CAR integration to oncogenesis is not clear. Here we report a case ...
ascopubs.org24 天
Results From First-in-Human Phase I Study of a Novel CD19-1XX Chimeric Antigen Receptor ...
Surrogate End Points for Overall Survival in Neoadjuvant Randomized Clinical Trials for Early Breast Cancer Twenty-eight patients underwent apheresis and received CAR T cells. Sixteen and 12 patients ...
The American Journal of Managed Care3 天
Geographic Barriers Impede Access to Novel Cancer Treatments
In the wake of novel bispecific and chimeric antigen receptor T-cell therapies for various cancers, geography still plays a big role in patients' abilities to receive such treatments.