Intraductal neoplasms of the bile duct are macroscopically characterized by exophytic or polypoid growth patterns and have a favorable prognosis. Although some tumors with a predominantly tubular ...

肝内胆管癌(intrahepatic cholangiocarcinoma, iCCA)的预后不佳，很大原因是由于诊断不够及时造成的，因此iCCA的早期诊断和及早治疗是提高疾病治愈效果的 ...

The aim of this study was to identify the pattern and significance of expression of p53 and PCNA in cholangiocarcinoma and primary sclerosing cholangitis. Histological sections from 18 patients ...

Chemoradiation combined with immunotherapy significantly boosts survival in patients with resected extrahepatic ...

Cholangiocarcinoma, also known as bile duct cancer, is a rare disease. It's a devasting condition incurable at the point ...

In a follow-up analysis to the pivotal TOPAZ-1 study, which established the combination therapy of durvalumab (an ...

Cholangiocarcinoma is a relatively rare adenocarcinoma of the bile ducts that is rapidly fatal unless it can be completely resected. In most cases, the tumor is too advanced for resection by the ...

Adjuvant chemoradiation combined with camrelizumab was well tolerated and yielded significantly improved long-term survival,” the researchers wrote.

Across the 3 cholangiocarcinoma subtypes, OS of more than 3 years was associated with lower percentages of PD-1+ cells among the CD8+ T cells than those with OS of less than 3 years.

The “ubiquitous dependency” of cholangiocarcinoma on CDK4/6 activity, Kongpetch said, suggests that the that the CDK4/6-pRB pathway could be a treatable target.

Background: Tinengotinib, a spectrum-selective multi-kinase inhibitor with unique binding properties to FGFR, potently inhibited FGFR2 fusion/rearrangement and acquired resistant/gatekeeper mutations ...