CRISPR construct to genetically ablate the GABA transporter GAT3 in the mouse visual cortex, with effects on population-level neuronal activity. This work is important, as it sheds light on how GAT3 ...

In the brain, not all blood flow is created equal. RIKEN researchers have developed a detailed cortical layer map of the ...

Throughout the brain's cortex, neurons are arranged in six distinctive layers, which can be readily seen with a microscope. A team of MIT neuroscientists has now found that these layers also show ...

Recording from individual cortical layers has been difficult in the past, because each layer is less than a millimeter thick, so it's hard to know which layer an electrode is recording from.

Cortical Interneurons Show Layer-Specific Activities. Researchers examine the firing patterns of interneurons throughout all layers of the somatosensory cortices of alert mice.

Our work finds that similar synaptic dysfunctionalities and hyperexcitable phenotypes occur more pronouncedly in the superficial rather than the deep layers of the human cortex (Gazestani et al., 2023 ...

A new study finds key differences in the development of the cortex between autistic boys and girls ages 2-13. The study found sex-specific changes in the thickness of the outer layer of the brain ...