Aziridine-containing cyclic tetrapeptides possess great potential for covalent protein labeling and can be valuable in screening libraries. Chung et al. describe the synthesis, cyclization, and ...

Elucidation of the cyclization mechanism catalyzed by terpene synthases is important for the rational engineering of terpene cyclases. We developed a chemoenzymatic method for the synthesis of ...

Cyclization In Close Quarters March 24, 2008 1 min read A version of this story appeared in Volume 86, Issue 12 Share; The Diels-Alder reaction, a widely ...