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这种蛋白质称之为法尼醇X受体(FXR,farnesoid X receptor),其能帮助控制消化脂质的胆汁酸的产生,FXR能和胆汁酸协同工作,在维持机体健康肠道上 ...
Farnesoid X receptor (FXR) gene deficiency impairs urine concentration in mice. The farnesoid X receptor (FXR) is a ligand-activated transcription factor belonging to the nuclear receptor superfamily.
Oncogene - Farnesoid X receptor inhibits tamoxifen-resistant MCF-7 breast cancer cell growth through downregulation of HER2 expression Skip to main content Thank you for visiting nature.com.
Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...
Researchers assessed the association between farnesoid X receptor (FXR) inhibition and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.
Farnesoid X receptor is a member of the ligand-activated nuclear hormone receptor superfamily. It functions as heterodimer with retinoid X receptor and binds genomic DNA of the target genes ...
The expression and activity of Cystathionase is reduced in rodent models of liver injury, leading to hyper-homocysteinemia and impaired generation of hydrogen sulphide, two factors that contribute ...
The farnesoid-X receptor (FXR), also known as the chief regulator of bile acid metabolism, is thought to play a role in some hepatobiliary and gastrointestinal disorders. A recent study has ...
The FDA has granted Fast Track designation to TERN-101 (Terns Pharmaceuticals) for the treatment of non-alcoholic steatohepatitis.
The farnesoid-X receptor (FXR), also known as the chief regulator of bile acid metabolism, is thought to play a role in some hepatobiliary and gastrointestinal disorders. In a study published in ...