We restrict life's possibilities to a narrow subset of choices; we tend to omit some of the most important objectives, and we’re not good at estimating the probability of certain outcomes.

An important one is that patients may be exposed to a highly toxic dose. To solve this problem, escalation with overdose control was proposed by Babb et al 31 ( Fig. 1 ). In escalation with overdose ...

Spring practice is right around the corner for Notre Dame, and the Fighting Irish defense will look to build on last season's regular success while looking to wash away the stench of the bowl game.