Intrasplenic transplantation of IL-18 gene-modified hepatocytes into S. japonicum-infected mice could result in a significantly increased IFN-γ and IL-2 but decreased IL-4 and IL-10 concentration ...

The intrasplenic bolus passes along the portal vein and reaches the right side of the heart via the liver or the portal collateral vessels, its route is then identical to the peripheral venous ...

During these changes, plasma volume and intrasplenic pressure rose progressively; ascitic-fluid pressure also rose, but the rise was considerably less than that in intrasplenic pressure.

We then performed AAV vector liver delivery in adult C57/BL10 mice by intrasplenic infusion, which is an easy and less-invasive alternative route to achieve portal vein delivery and has been used ...