Synthesis of N-β-brominated alkenyl isothiocyanates via dehydrogenation of alkyl isothiocyanates. Journal: Chemical Communications Published: 2024-06-06 DOI: ...

Isothiocyanates, naturally occurring compounds derived from glucosinolate precursors in cruciferous vegetables, have emerged as promising agents in cancer chemoprevention.

Isothiocyanates, such as sulforaphane, are known for their potent anti-cancer and anti-inflammatory properties. The enzyme myrosinase is responsible for this conversion, but it is often destroyed ...

Protein shakes and bicarbonate of soda are some of the more popular nutritional strategies to boost fitness, but the latest ...

Protein shakes and bicarbonate of soda are some of the more popular nutritional strategies to boost fitness, but the latest ...

Isothiocyanates are the principal irritant constituents of the mustard oils found in many members of Brassicaceae (previously Cruciferae), the mustard family.

High-Pressure Processing of Broccoli Sprouts: Influence on Bioactivation of Glucosinolates to Isothiocyanates. Journal of Agricultural and Food Chemistry, 2017; DOI: 10.1021/acs.jafc.7b01380; ...

This report describes the oxidative metabolism of isothiocyanates to isocyanates catalyzed by rat liver microsomes. Incubation of 2-naphthylisothiocyanate, microsomes, and NADPH yielded either N,N′-di ...

Chemopreventive isothiocyanates selectively depletes mutant p53 in tumor cells Peer-Reviewed Publication. Georgetown University Medical Center. Denver, Colo. ...

Broccoli and broccoli sprouts have the highest amount of the isothiocyanates. "Our paper focuses on the anti-cancer activity of one of these compounds, called sulforaphane, or SFN," Azarenko added.

Researchers at Lombardi Comprehensive Cancer Center at Georgetown University Medical Center have demonstrated that naturally-occurring compounds can selectively deplete mutant p53 and restore ...