Multicentric Castleman disease (MCD) comprises a heterogenous group of rare disorders that exhibit generalized symptoms such as swelling of lymph nodes, anemia, fever, and fatigue.

A group of researchers from Okayama University, Japan, developed a definition for an aggressive subtype of the idiopathic multicentric Castleman disease (iMCD), which shows symptoms of ...

Castleman disease is a condition that involves noncancerous enlargement of lymph node tissue. The more common type, unicentric, often does not produce symptoms. In contrast, multicentric, the less ...

Multicentric Castleman disease. If you have MCD, you'll need treatment that works throughout your body, because the disease has spread to many lymph nodes.

Prognostic impact of multifocal and multicentric breast cancer compared with unifocal breast cancer. Authors : Atsushi Fushimi , Atsushi Yoshida , Hiroshi Yagata , Osamu Takahashi , Naoki Hayashi , ...

The use of breast-conservation surgery in multicentric breast cancer (i.e., cancer in more than one quadrant) is controversial. Historically, these patients were thought to be candidates for ...

KSHV-associated multicentric Castleman’s disease is a B-cell lymphoproliferative disease characterized by inflammatory symptoms, including high fevers, night sweats, cachexia, and weight loss ...

Diagnosis COX2-related multicentric mixed-type Castleman's disease. Management Chemotherapy and COX2 inhibitors. Background A 34-year-old male presented with a 5-month history of fatigue, ...

Multicentric breast cancer has been considered to be a contraindication for sentinel node (SN) biopsy (SNB). In this prospective multi-institutional trial, SNB-feasibility and accuracy was evaluated ...