Cell Death & Differentiation - Inhibition of neddylation by MLN4924 improves neointimal hyperplasia and promotes apoptosis of vascular smooth muscle cells through p53 and p62 Skip to main content ...

Neointimal and Tubulointerstitial Infiltration by Recipient Mesenchymal Cells in Chronic Renal-Allograft Rejection. Authors: Paul C. Grimm, M.D., Peter Nickerson, ...

Background: Neointimal hyperplasia of vascular smooth muscle cells (VSMCs) is caused by increased proliferation and decreased apoptosis. We previously reported that alpha-lipoic acid (ALA), a ...

At six months, the degree of neointimal proliferation, manifested as the mean (±SD) late luminal loss, was significantly lower in the sirolimus-stent group (–0.01±0.33 mm) than in the standard ...

Early in vivo studies in mice suggest sulindac, a nonsteroidal anti-inflammatory drug already used to induce regression of colon polyps, may prevent neointimal proliferation after arterial injury ...

At 6 months, less neointimal hyperplasia was found at both the proximal and distal anastomoses. This included the prosthetic wall, suture region, and arterial wall.

In the EGO-COMBO study, a dual-therapy endothelial progenitor cell-capturing sirolimus-eluting stent achieved exceptional late neointimal regression, rendering favorable 36-month clinical results ...

OCT documented that the patients receiving the COMBO stent achieved neointimal regression from 9 months to 24 months. A reduction of in-stent percentage neointimal volume, which Lee said is “the most ...