Children who develop neuroblastomas, a rare form of cancer which develops in nerve cells, may benefit from receiving certain anti-tumor drugs as well as chemotherapy, a new trial has found.

These kinds of neuroblastomas can be classified into three distinct subgroups, each demonstrating unique prognostic implications and varying vulnerabilities to investigational therapies." ...

Neuroblastomas have a wildly varied spectrum of clinical behavior that ranges from spontaneous regression to progressive disease and metastasis, report Drs. Yu-Feng Guo and Shi-Cang Yu.

The largest single cell study to date of the childhood cancer, neuroblastoma, has answered important questions about the genesis of the disease. The researchers from the Wellcome Sanger Institute, ...

What sounds contradictory at first glance, namely firing a tumor with a growth factor, makes sense in neuroblastoma. Neuroblastoma is a tumor of the peripheral nervous system and the most common solid ...

Neuroblastomas are characterized by 1p deletions, suggesting that a tumor suppressor gene (TSG) resides in this region. We have mapped the smallest region of deletion (SRD) to a 2 Mb region of ...

Neuroblastomas are embryonal tumours of the sympatho-adrenal lineage with a clinical course ranging from spontaneous regression to fatal progression. The Phox2B homeobox transcription factor ...

For over a century, researchers have noted that neuroblastomas exhibit diverse and often dramatic clinical behaviors (). (For a timeline of the major advances in neuroblastoma research, see the ...

Of 340 eligible participants, 190 underwent resection, 57 were treated with chemotherapy, and 93 were observed with gross residual tumor. Of those 93 patients with unresected tumors, spontaneous ...

Localized Infant Neuroblastomas Often Show Spontaneous Regression: Results of the Prospective Trials NB95-S and NB97 Barbara Hero , Thorsten Simon , Ruediger Spitz , Karen Ernestus , Astrid K. Gnekow ...

A protein produced by nerve cells appears to be elevated in the blood of those with an aggressive form of neuroblastoma. The finding, published online October 12 in the American Journal of ...

Fighting neuroblastomas by blocking DNA replication, repair. ScienceDaily . Retrieved June 2, 2025 from www.sciencedaily.com / releases / 2014 / 04 / 140416101339.htm ...