Purpose: Familial ovarian cancer is most often associated with hereditary breast and ovarian cancer, implicating mutations in the BRCA1 and BRCA2 genes. Hereditary nonpolyposis colorectal cancer ...

Hereditary nonpolyposis colorectal cancer is caused by a germ-line mutation in any of the mismatch-repair genes listed in Table 2. As of this writing, two genes, ...

PURPOSE: Germline mutations in mismatch repair genes predispose to hereditary nonpolyposis colorectal cancer (HNPCC). To address effective screening programs, the true incidence of the disease must be ...

PURPOSE: Hereditary nonpolyposis colorectal cancer (HNPCC) is an autosomal dominant disease characterized by the clustering of colorectal cancer, endometrial cancer, and various other cancers. The ...

April 26, 2005 — Genetic testing facilitates the diagnosis of hereditary nonpolyposis colorectal cancer (HNPCC), according to the results of two studies published in the April 27 issue of JAMA ...

Women with the Lynch syndrome (hereditary nonpolyposis colorectal cancer) have a 40 to 60 percent lifetime risk of endometrial cancer and a 10 to 12 percent lifetime risk of ovarian cancer. The ben ...

Hereditary nonpolyposis colorectal cancer increases a person’s risk of developing colorectal cancer where polyps are either very small or not present at all.