In this Review, familial and sporadic neurological disorders reported to have an etiological link with DNA repair defects are discussed, with special emphasis placed on the molecular link between ...

Clinical diagnosis of mismatch repair defects has recently been complicated by the discovery of multiple gene alterations that lead to an expanded tumor spectrum. Studies of mismatch repair ...

A number of these disorders have a definitive link to an inherited or acquired defect in one of the DNA repair pathways. Table 1 lists these disorders along with the known genetic DNA repair ...

Many children have no symptoms. So this defect may not be found until a child is older or becomes an adult. Heart defect repair is surgery to fix a heart problem that prevents blood from flowing as it ...

Heart defect repair is surgery to fix a heart problem that prevents blood from flowing as it should through the heart. The doctor will make a large cut in your chest. The cut is called an incision. It ...

Now five months old, her son, Maxley, will undergo surgery in mid-December to repair a birth defect in his heart. “He’s doing great, so they’re able to wait a little bit longer, which is ...

An orthopaedic surgeon discusses how this approach helps alleviate pain caused by joint injuries and chronic conditions.