The ribosome is a large assembly of proteins and ribosomal RNAs (rRNAs) that functions to translate messenger RNAs (mRNAs) into proteins. The ribosome catalyzes the assembly of amino acids into ...

引言在我们体内，数以亿计的细胞每天都在进行着极其复杂的生命活动，其中翻译过程扮演着至关重要的角色。翻译是基因表达的最后一步，它通过核糖体（ribosome）将mRNA上的遗传信息转化为蛋白质，驱动细胞的功能。然而，尽管翻译过程已经被广泛研究，研究人员却一直未能完全解开一个关键谜团：多个核糖体如何协同工作来高效地 ...

1 First, the researchers generated stopless-ORF circular RNAs (socRNAs) that promoted continuous translation for extended periods of time. The researchers visualized translation, including ribosome ...

However, the infection did modify the underlying molecular structure of the ribosome, leading to increased poxvirus protein translation. Genetic knockout screens coupled with metabolic assays ...

A new technique reveals ribosome cooperativity, providing new insights into protein production. Researchers from Marvin Tanenbaum’s group at the Hubrecht Institute (Utrecht, Netherlands) have ...

A previously unknown kind of ribosome is responsible for folding sperm proteins, which decay before fertilization if prepared by other ribosomes. Dan is a News Editor at The Scientist. He writes and ...

Researchers at University of Tsukuba have developed a new model that simulates the internal environment of a ribosome—the cellular site of protein synthesis. Using computer simulations ...

ReAberrant translation initiation at non-AUG start codons is associated with cancer and neurodegenerative diseases. Therefore, identifying how non-AUG translation is regulated differently from ...

He ripped the ribosome open, literally. And, it became an important step in the production of antibiotics. In 2000, using a method known as x-ray crystallography, Venkatraman Ramakrishnan and ...

Thermo-sensitive genic male sterility 5 (tms5) is a widely used thermo-sensitive genic male sterile (TGMS) line for two-line ...