Sixty patients received at least 1 dose of either study agent; the majority (65%) were treatment naïve. The ORR for the overall population was 33% and 50% in patients with clear cell RCC with ...

Patients who had mRCC with sarcomatoid features in the primary tumor and who were treated with VEGF-targeted therapy were retrospectively identified. Pathology slides were reviewed to determine the ...

How the study was designed. Data from 709 patients with mRCC, with or without sarcomatoid features, diagnosed between January 2011 and December 2022 were extracted from the prospective Canadian ...

“Sarcomatoid tumors are highly resistant to anti-cancer therapies, and many patients run out of available treatment options. Our findings here might have unveiled a druggable ‘Achilles Heel ...

Sarcomatoid carcinoma is generally a biphasic malignant tumor demonstrating morphological and/or immunohistochemical evidence of epithelial and mesenchymal differentiation, authors observed.

Similarly, sarcomatoid RRC also has higher expression of PD-L1, which likely accounts for better PFS with sarcomatoid features. The finding of diminished PFS with intermediate MSKCC risk scores, ...

Doctors in a meeting (Getty Images) Researchers have reported findings from the largest cohort of sarcomatoid renal cell carcinoma to date. Sarcomatoid renal cell carcinoma (RCC) often presents in ...

Sarcomatoid carcinomas are made up of both carcinoma - cancer of the epithelial tissue, which lines organs - and sarcoma - cancer of connective tissues like bones.

Intrahepatic sarcomatoid cholangiocarcinoma: A case report of the youngest patient on record and a review of the condition's characteristics. Front Surg . Published online September 1, 2022. doi ...