The Lancet on the anti-IL-5 antibody mepolizumab in individuals with allergic asthma, evidence has accumulated that the pathogenetic role of eosinophils is fundamentally different between asthma ...

Endoscopy in paediatric patients presents unique challenges due to the vulnerability of young children and the need for procedures under deep sedation or general anaesthesia.1 Furthermore, indications ...

In 2025 the US Federal Government has attacked scientific research and evidence, medical expertise, public health, health equity, and human rights.1–5 At this challenging time, many health ...

Tuberculosis remains the world's leading infectious killer, resulting in more than 1·25 million deaths in 2023 alone.1 During ...

Childbirth can be a defining life experience, but it can also be disempowering for many women. The UK Health Secretary, Wes ...

Solid organ transplantation provides life-saving and life-enhancing treatments for patients with end-stage organ failure.1,2 ...

Growing interest in health and the exposome—a person's collective environmental exposures—is spurring new funding and research initiatives. Talha Burki reports.

We thank Dongli Zhao and colleagues and M Hossein Nowroozzadeh for their helpful comments on our Article1 reporting the results of the STAR study, a randomised controlled trial of stereotactic ...

Negotiations are ongoing in New York to agree the latest UN political declaration on non-communicable diseases (NCDs) and ...

Digital health interventions (DHIs) show promise for the treatment of mental health disorders. However, existing ...

Since the emergence of the Zika virus epidemic in 2014 and the associated novel sequalae that emerged, much has been learned about the effects of antenatal exposure to Zika virus. Zika virus in ...

The relationship between hormone therapy (oestrogen with or without progestogen) and breast cancer risk has been widely ...