Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers successfully removed extra copies of chromosome 21 in Down syndrome cell lines, ...

A century after Down syndrome was first described, scientists discovered that the root cause of this disorder is a condition called trisomy 21. What strides in research have been made since then?

This shows maternal-age-specific estimates of trisomy among all clinically recognized human pregnancies, generated by combining data from individual trisomies and assuming a spontaneous abortion ...

Down syndrome, or trisomy 21, is caused by the presence of a third copy of the 21st chromosome. Affected individuals have ...

Gene editing techniques may eventually allow trisomy to be treated at the cellular level, according to an in vitro ...

Recognition of the clinical features of Trisomy 13 syndrome, a common autosomal trisomy, provides the basis for diagnostic testing and counseling of families. This article provides a systematic ...

CRISPR Technology Shows Promise in Removing Extra Chromosomes in Down SyndromeGene editing techniques may eventually allow ...

Harley was born prematurely with Trisomy 18, a chromosome disorder leaving her with three 18th chromosomes in a cell instead of the normal two. The extra chromosome results in congenital ...

Numerical chromosomal abnormalities (aneuploidies) -- the presence of an extra chromosome (trisomy) or a missing chromosome (monosomy) -- result from segregation errors during cell division ...