Xenografted human CLL cells preferentially reside and proliferate in the SP of NSG mice. We injected 1 × 10 8 human PBMCs from CLL patients into NSG mice and obtained repeat blood counts. After 1 ...

In September 27 Science, Melanie Snow and colleagues from Monash University, Victoria, Australia, show that fertile adult mice can be generated from xenografted murine ovaries (Science, 297:2227, ...

Relative to xenografted control mice, or to ungrafted APP-KI mice, the APP-KI mice hosting human neurons had elevated p-tau181 and p-tau231 in their plasma. This suggested that, when faced with ...

Radiofrequency ablation (RFA) is the most common curative alternative. Dbait are new molecules that inhibit DNA double-strand breaks repair. In vitro, Dbait has shown to increase cell death after ...

Since microglia play a critical role in resolving amyloid pathology and it has been previously demonstrated that microglia function can be induced by TREM2 activation, TREM2 agonism has been ...