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4月
EBF1 活性决定 CD22 转录及白血病对奥加伊妥珠单抗(InO)敏感性 ...
在淋巴恶性肿瘤治疗中,奥加伊妥珠单抗(InO)虽对 B 细胞急性淋巴细胞白血病(B-ALL)疗效高,但 CD22 表达及白血病对 InO 敏感性的影响因素不明。研究人员通过多组学分析等,发现 EBF1 是 CD22 表达关键调节因子,影响 InO 疗效,为精准治疗提供依据。 在白血病 ...
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