Finally, 10 years on, the trilogy is complete. Patrick Tam and Janet Rossant, two of the most respected mouse developmental biologists, have produced an exceptional book. Right from the outset, it ...

The chromatin-bound proteome of embryonic stem cells transitioning to 2C-like cells uncovers chromatin regulators involved in heterochromatin formation.

Unlike organoids, which model parts of single organs, the duo coaxed aggregates of mouse embryonic stem cells to carry out fundamental processes of development to become embryo-like entities, or ...

Three-dimensional visualization of nerves (green) and blood vessels (magenta) in a mouse embryo. Developmental biologist Kat Hadjantonakis works to gain insights into the critical events that direct ...

More information: Jiajia Ye et al, Nutrient deprivation induces mouse embryonic diapause mediated by Gator1 and Tsc2, Development (2024). DOI: 10.1242/dev.202091 ...

Asingle type of mouse stem cell can generate a structure in culture capable of self-organizing to generate both embryonic cells and those that are the precursor to the placenta, according to a study ...

It’s a new way to create “bi-paternal” mice that can survive to adulthood—but human applications are still a long way off.

A team of stem cell scientists have successfully used embryonic stem ... at some point during development due to these genes." Earlier attempts to make a bi-paternal mouse used ovarian organoids ...

Early embryo development is a highly dynamic process that is of great interest to scientists, but most studies tend to focus on a single species, typically mouse or human. This study, however ...

A team of stem cell scientists have successfully used embryonic stem ... at some point during development due to these genes." Earlier attempts to make a bi-paternal mouse used ovarian organoids ...