MIT neuroscientists have made a breakthrough in treating fragile X syndrome by leveraging a novel neurotransmitter signaling ...

在慢性疼痛过程中脊髓背角区（SDH）的星形胶质细胞增生比神经损伤后的小胶质细胞增生更明显。为探究SDH区星形胶质细胞Gpr37l1是否参与疼痛，研究人员首先通过单细胞测序发现Gpr37l1富集表达SDH区星形胶质细胞，免疫荧光实验证实Gpr37l1可 ...

Members of the nuclear receptor superfamily of transcription factors have important roles in modulating the responses of macrophages, microglia and lymphocytes to pro-inflammatory signalling ...

Furthermore, electrophysiological and immunohistochemical data suggest that glutamate receptors may be subject to rapid exo- and/or endocytosis, demonstrating that the biochemical composition of ...

Researchers have shown that as flies encounter an odor signal, the specific pattern of interference between olfactory receptors helps flies quickly compute the “gist” of the odor’s meaning.

These are expressed by neurons in the animals’ antennae and maxillary palps (small appendages near their mouths). Early research had suggested that each neuron expresses just one type of receptor, and ...

A neuroanatomical minimal network model was revisited to elucidate the mechanism of salt concentration memory-dependent chemotaxis observed in Caenorhabditis elegans. C. elegans memorizes the salt ...

Scientists think ketamine relieves depression and anxiety by altering GluN1-2B-2D’s movements, but the effects can vary ...

Researchers were able to tag neuronal populations that express nIL-1R1 using a clever cell tagging approach, offering new insights into the functional roles of this receptor in the central nervous ...

Olfaction in mammals is mediated by a population of olfactory sensory neurons, each of which expresses just one of ~1000 olfactory receptor proteins that are encoded in the genome. Olfactory activity ...