The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

University of Western Australia research reveals how cells convert physical exercise forces into energy production responses.

The Golgi body (or Golgi complex, apparatus), and Endoplasmic reticulum (ER) are both organelles found in the majority of eukaryotic cells. They are very closely associated and show both ...

Scientists at the University of Western Australia and the Perron Institute for Neurological and Translational Science have ...

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The endoplasmic reticulum is the protein-making factory within cells consisting of tightly stacked sheets of membrane studded with the molecules that make proteins. Now, researchers have refined a ...

The endoplasmic reticulum plays a more important role in type 2 diabetes and its complications than previously believed, new research suggests. To make their discovery, scientists identified ...

Calreticulin was discovered in skeletal muscle cells in 1974. Thomas Ostwald and David MacLennan were characterizing proteins that bind to calcium in the sarcoplasmic reticulum — a specialized ...

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This calcium activates another ion channel called ryanodine receptor (RyR1 in muscle cells) which releases even more calcium stored inside the sarcoplasmic reticulum to the cytoplasm of the cell.

EMITT-1: Proof-of-mechanism immunopeptidome (ImPD) effects at target PK exposure, in a phase 1 study of GRWD5769 (a first-in-class inhibitor of Endoplasmic Reticulum Aminopeptidase 1 [ERAP1]) in ...