Identification of a nitric oxide-regulated transitional state of Müller glia reveals a key mechanism enabling neuronal regeneration in the injured vertebrate retina.

High-profile news coverage that eLife papers generated in October 2025, including NPR, One Earth and Neuroscience News.

Recombination serves as a pivotal force propelling the evolution of genomic diversity in sexually reproducing organisms. Despite its fundamental role, the evolutionary dynamics of recombination rates ...

The authors present convincing data to validate abscisic acid-induced dimerisation to induce a synthetic spindle assembly checkpoint (SAC) arrest that will be of particular importance to analyse ...

Trained immunity provides a unifying framework linking innate immune memory to both protective and maladaptive inflammation ...

Researchers have mapped the cellular diversity of the eye’s fluid drainage tissue, uncovering a cell subtype that may contribute to glaucoma progression and respond to vitamin B3 treatment.

The ReproSci project retrospectively analyzed the reproducibility of 1006 claims from 400 papers published between 1959 and 2011 in the field of Drosophila immunity. This project attempts to provide a ...

eLife reviews research spanning allergy, immunity and immunoregulation, inflammation and T-cell receptor signalling. Learn more about what we review and sign up for the latest research.

Single-cell transcriptomics identifies three discrete mouse trabecular meshwork subtypes and demonstrates that an Lmx1b glaucoma mutation drives mitochondrial dysfunction and elevated intraocular ...

This important study builds on previous work from the same authors to present a conceptually distinct workflow for cryo-EM reconstruction that uses 2D template matching to enable high-resolution ...

The mean, variance, and autocorrelation of glucose dynamics are independently associated with coronary plaque vulnerability.

Proteomics experiments on Drosophila reveal sex-specific effects in aging, and an important role for a protein called DIP-β.