Stroke is the second‐leading cause of death globally and ischemic stroke constituted more than 60% of all incident strokes in 2019. 1 Intravenous alteplase thrombolysis was approved by the US Food and ...

BACKGROUND: Thromboembolic events, including myocardial infarction (MI) or stroke, caused by the rupture or erosion of unstable atherosclerotic plaques are the leading cause of death worldwide.

Stroke is a disease of disparities, with tremendous racial and ethnic inequities in incidence, prevalence, treatment, and outcomes. The accumulating literature on the relationship between stroke and ...

Writing committees are instructed to consider the methodology of performance measure development 1, 2 and to ensure that the measures developed are aligned with AHA/ACC clinical practice guidelines.

Purpose— Our goal is to provide an overview of the current evidence about components of the evaluation and treatment of adults with acute ischemic stroke. The intended audience is physicians and other ...

Non–vitamin K oral anticoagulants (NOACs) are now widely used as alternatives to warfarin for stroke prevention in atrial fibrillation and management of venous thromboembolism. In clinical practice, ...

Valvular repair or replacement is a common final management option in both primary and secondary MR, resulting in ≈50 000 annual mitral valve operations in the United States; however, defining the ...

As early as 1699, Chemineau described a heart composed of 2 auricles but only 1 ventricle.1 The univentricular heart has since fascinated the medical community. Unique in its complexity and scope, the ...

Despite the controversy, it is now well recognized that mitral valve prolapse poses a significant disease burden and is a major contributor to cardiovascular morbidity and mortality. Based on the ...

The past decade has seen increasing interest in the tricuspid valve (TV), once referred to as the forgotten valve, as a result of a combination of improved imaging and therapeutic possibilities plus a ...

AIM The “2023 ACC/AHA/ACCP/HRS Guideline for the Diagnosis and Management of Atrial Fibrillation” provides recommendations to guide clinicians in the treatment of patients with atrial fibrillation.

To further investigate a role for proteases in plaque rupture, we have developed a transgenic mouse model in which the human scavenger receptor promoter drives macrophage-specific overexpression of ...