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红斑狼疮研究新突破!浙大团队发现,一类突变是疾病重要驱动因素
长期以来,尽管遗传因素在SLE的发病中的重要作用已是共识,但其确切作用始终未得到揭示。近年来,数个遗传学研究表明单基因突变即可导致SLE,单基因狼疮的概念呼之欲出。然而临床上数量庞大的SLE患者得到明确遗传学解释的仍然是少数,这提示SLE发病的遗传基 ...
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